Assignment 1: Investigate the immunopathology of rheumatic fever (RF) and rheumatic heart disease (RHD) and provide an analysis of the role of infection with Streptococcus pyogenes as a risk factor.

Assignment 1

Investigate the immunopathology of rheumatic fever (RF) and rheumatic heart disease (RHD) and provide an analysis of the role of infection with Streptococcus pyogenes as a risk factor. (20% weighting)



  1. Abstract (200 words limit)
  2. Introduction
  3. General content
  4. Conclusion (150 word limit)
  5. References (Harvard referencing)

1. Abstract 

Please use the full word limit (but not exceed it) to provide a succinct summary of the essence of the report, including such items as impact of the disease and principal findings. Please avoid indicating what is to follow in the report, as these comments are best placed as the last sentences at the end of the introduction.

2. Introduction

The introduction should include a broad description of the nature of RF and RHD, epidemiological factors such as incidence, significance, and impact on the community of such as health costs and patient wellbeing (morbidity/mortality).

3. General content

a. Your assignment needs to address each of the following topics that relate to aspects of RF and RHD. Please note that you must use the sub- headings that I have provided below.

The principal reason is that this will ensure that you cover the essential items related to understanding the syndromes and will also correlate with the assessment emphasis (marks allocated) as described in the attached Marking Schedule.

In this assessment, I also seek to develop your skills in researching and presenting manuscripts that will add to your training in authoring research journal articles.

b. Provided sub-headings

Your case study must cover the following aspects of RF and RHD

  • Clinical features and risk factors

That is, what are the clinical features and risk factors for developing of RF and RHD?

  • Pathology

That is, what is known about the pathophysiology that results in outcomes of these diseases?

  • Control and prevention

What are the range of measures used to control and/or prevent these diseases?

4. Conclusion

(About 150 words, but less strict on the word count than the Abstract)

Please avoid repeating the Abstract. Try and provide a reflective statement on
the disease, challenges that face clinicians and possible future research directions that may assist diagnosis and therapeutic options.

5. References.

Please ensure that any statements that have been made from your readings are cited and supported in the reference list. Please use the Harvard system.


It is highly recommended that you include images and/or tables to illustrate and support statements. Ensure that below the image you enter its source reference and a short statement (termed an annotation) as to what it illustrates. The images and tables used should also be referred to in the body of the text.

Please proof-read for grammatical errors and typos.

Please read my guidelines on writing assignments available on StudyDesk.

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